Co-crystals of duloxetine and cox-inhibitors for the...

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 333/20 (2006.01) A61K 31/192 (2006.01) A61K 31/381 (2006.01) A61K 31/40 (2006.01) A61P 25/04 (2006.01) A61P 29/00 (2006.01) C07C 59/64 (2006.01) C07D 207/337 (2006.01)

Patent

CA 2724812

The present invention relates to co-crystals of duloxetine and co-crystal formers selected from COX-INHIBITORs, processes for preparation of the same and their uses as medicaments or in pharmaceutical formulations, more particularly for the treatment of pain. Specific COX-INHIBITORS are naproxen and tolmetin.

La présente invention concerne des co-cristaux de duloxétine et des agents de formation de co-cristaux choisis parmi les inhibiteurs de COX, des procédés pour leur préparation et leurs utilisations comme médicaments ou dans des formulations pharmaceutiques, plus particulièrement pour le traitement de la douleur. Les inhibiteurs de COX spécifiques sont le naproxène et la tolmétine.

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