Co-expression of recombinant proteins

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/70 (2006.01) C07K 14/285 (2006.01) C07K 14/315 (2006.01) C12N 15/63 (2006.01)

Patent

CA 2410337

Expression vectors are described which permit the recombinant expression of proteins which essentially contain, in addition to nucleic acid encoding the recombinant protein, nucleic acid encoding a non-proteolytic analog of Haemophilus Hin47 protein, with or without leader sequence, or nucleic acid encoding high molecular weight proteins of non-typeable Haemophilus, which are hmwB, hmwC or hmwBC.

Cette invention concerne des vecteurs d'expression permettant la recombinaison de protéines qui renferment, pour l'essentiel, ou un acide nucléique codant pour la protéine recombinante, un acide nucléique codant pour un analogue non protéolytique de la protéine <i>Haemophilus</i> Hin47, avec ou sans séquence de tête, ou un acide nucléique codant pour des molécules à poids moléculaire élevée de <i>Haemophilus</i> non typable, qui sont <i>hmwB</i>, <i>hmwC</i> or <i>hmwBC</i>.

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