Coarse spray delivery of functional biologic materials

Details Coarse spray delivery of functional biologic materials Coarse spray delivery of functional biologic materials

A - Human Necessities

61

M

A61M 11/00 (2006.01) A61K 9/12 (2006.01) A61K 35/76 (2006.01) A61K 45/00 (2006.01) A61K 47/10 (2006.01) A61M 13/00 (2006.01) A61M 15/00 (2006.01) A61M 16/00 (2006.01) A61P 25/20 (2006.01) A61P 29/00 (2006.01) A61P 31/04 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) A61P 37/04 (2006.01) A61P 37/06 (2006.01) A62B 7/00 (2006.01) A62B 9/00 (2006.01) A62B 18/00 (2006.01)

Patent

CA 2218879

The present invention relates to a method of introducing biologic materials into the conducting airways of the bronchial system. The invention involves the use of a liquid carrier or suspension for the biologic materials, delivered in relatively large droplet form at a velocity greater than the air velocity of the normally breathing subject. This method also can be used for localized delivery of such biologic materials, including diagnostic and imaging agents, into other gas-filled body cavities.

La présente invention concerne un procédé pour introduire des produits à usage biologique dans les voies aérienne des bronches. Selon l'invention, on utilise un agent de suspension ou un vecteur liquide pour le produit à usage biologique, administré sous la forme de gouttelettes relativement grandes, à une vitesse supérieure à la vitesse de l'air d'un sujet respirant normalement. Ce procédé peut également être utilisé pour l'administration locale dans d'autres cavités du corps remplies d'air, de produits à usage biologique tels que des agents diagnostiques et des agents pour imagerie.

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