Coated adhesive tablets

Details Coated adhesive tablets Coated adhesive tablets

A - Human Necessities

61

K

167/164, 167/260

A61K 47/00 (2006.01) A61K 9/00 (2006.01) A61K 9/28 (2006.01) A61K 31/00 (2006.01) A61K 31/195 (2006.01)

Patent

CA 2006771

4- 17398/+ Coated adhesive tablets Abstract of the Disclosure The invention reelates to a pharmaceutical composition for the applicationof baclofen, in the form of an adhesive tablet, to the mucosa in the oral cavity, which pharmaceutical composition comprises a) a hydrophilic tablet core, the top surface of which adheres to the receptor surface of the oral mucosa and which contains the drug baclofen or a pharmaceutically acceptable salt thereof and, as excipients, a swellable vinyl polymer, a galactomannan and/or a pharmaceutically acceptable wax and/or a glyceride or completely or partially hydrogenated glyceride, and further optional excipients, and, if desired, b) a hydrophobic coating which covers the tablet core a), with the exception of the surface provided for the release of baclofen. The invention further relates to a process for the preparation of this adhesive tablet and the therepeutic use thereof as spasmolytic.

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