Coated bioabsorbable beads for wound treatment

Details Coated bioabsorbable beads for wound treatment Coated bioabsorbable beads for wound treatment

A - Human Necessities

61

L

A61L 27/00 (2006.01) A61K 9/16 (2006.01) A61K 9/50 (2006.01) A61L 15/32 (2006.01) A61L 15/64 (2006.01) A61L 26/00 (2006.01) A61L 27/44 (2006.01)

Patent

CA 2248848

The invention provides a material for use in a wound dressing or wound implant, the material comprising a plurality of beads, wherein each bead comprises a porous core of a first bioabsorbable material and a substantially non-porous layer of a second bioabsorbable material around the core. The porous core is preferably a sponge formed by freeze-drying a liquid suspension of the first bioabsorbable material. The preferred diameter of the beads is 0.1-4.0 mm, and the beads are preferably dispersed in a liquid or solid matrix. The invention also provides a method of making beads for use in the materials of the invention.

L'invention porte sur un matériau utilisable dans un pansement ou un implant pour blessure, ce matériau étant constitué de plusieurs billes, comportant chacune un noyau poreux fait d'une première substance bio-absorbable et un revêtement sensiblement non poreux fait d'une seconde substance bio-absorbable enrobant ce noyau. Celui-ci constitue, de préférence, une éponge obtenue par la cryodessiccation d'une suspension liquide de la première substance bio-absorbable. Le diamètre préféré des billes est compris entre 0,1 et 4,0 mm et celles-ci sont, de préférence, dispersées dans une matrice liquide ou solide. L'invention porte également sur un procédé de fabrication de billes à utiliser dans les matériaux susmentionnés.

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