Coated biomaterials and methods for making same

Details Coated biomaterials and methods for making same Coated biomaterials and methods for making same

A - Human Necessities

61

L

167/327

A61L 27/00 (2006.01) A61L 27/32 (2006.01) A61L 27/34 (2006.01) A61L 27/40 (2006.01) A61L 27/54 (2006.01) A61L 27/56 (2006.01) A61F 2/00 (2006.01)

Patent

CA 2013420

Biomaterials useful for orthopedic and dental applications is disclosed. These materials have a base portion of calcium carbonate and a surface layer of a synthetic phosphate such as hydroxyapatite. The base portion may be a calcium carbonate structure having three-dimensional interconnected porosity such as may be found in porous skeletal carbonate of marine life, e.g. coral porites skeletal aragonite, or it may be porous or non-porous granules of calcium carbonate. A method for making the biomaterials is also disclosed. The synthetic phosphate surface is made using a hydroconversion reaction with a soluble or solubilized phosphate such as ammonium dibasic phosphate ((NH4)2HPO4).

L'invention porte sur des biomatières utiles pour des applications orthopédiques et dentaires. Ces matières sont composées d'une base de carbonate de calcium et d'une couche superficielle d'un phosphate synthétique, comme l'hydroxyapatite. La base peut avoir la structure du carbonate de calcium, avec une porosité tridimensionnelle interconnectée, comme celle que l'on retrouve dans les squelettes de carbonates poreux de la vie marine, notamment les aragonites formant le squelette des porites du corail, ou alors elle peut être constituée de granulés de carbonates de calcium poreux ou non poreux. L'invention présente également une méthode pour préparer les biomatières. La surface de phosphate synthétique est obtenue grâce à une réaction d'hydroconversion avec un phosphate soluble ou solubilisé, comme le phosphate d'ammonium dibasique ((NH4)2HPO4).

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