Coated formulations

Details Coated formulations Coated formulations

A - Human Necessities

61

K

A61K 9/16 (2006.01) A61K 9/50 (2006.01) A61K 31/137 (2006.01)

Patent

CA 2637444

A pharmaceutical composition of a drug which may have increased plasma concentrations due to the concomitant use of antacids has been developed which comprises coating with the pH-dependent dissolution, characterized by the rapid dissolution at acidic conditions (pH < 5.5) and very slow dissolution at higher pH values.

La présente invention concerne une préparation pharmaceutique d'un médicament qui peut entraîner une augmentation des concentrations plasmatiques du fait de l'utilisation conjointe d'antiacides, ladite préparation comprenant un enrobage à dissolution dépendante du pH, caractérisé par une dissolution rapide dans des conditions acides (pH < 5,5) et par une dissolution très lente à des valeurs de pH plus élevées.

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