Coated hyaluronic acid particles

Details Coated hyaluronic acid particles Coated hyaluronic acid particles

A - Human Necessities

61

L

A61L 27/20 (2006.01) A61K 9/16 (2006.01) A61K 31/728 (2006.01) A61L 27/58 (2006.01)

Patent

CA 2687983

The present invention generally relates to particles comprising hyaluronic acid, wherein the particles are coated or encapsulated with a coating. The coating preferably comprises a polymer, protein, polysaccharide, or combination thereof that decreases the rate of degradation of the hyaluronic acid once the particles are placed in an aqueous environment, such as inside mammalian skin. The compositions of the present invention comprising such coated hyaluronic acid are useful for soft tissue augmentation, and are particularly useful as dermal fillers.

La présente invention concerne, de manière générale, des particules comprenant de l'acide hyaluronique, les particules étant revêtues ou encapsulées avec un revêtement. Le revêtement comprend de préférence un polymère, une protéine, un polysaccharide ou une combinaison de ceux-ci qui diminue la vitesse de dégradation de l'acide hyaluronique une fois les particules placées dans un environnement aqueux, tel qu'à l'intérieur de la peau d'un mammifère. Les compositions de la présente invention comprenant un tel acide hyaluronique revêtu sont utiles pour l'augmentation des tissus mous, et sont particulièrement utiles en tant que charges dermiques.

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