A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/28 (2006.01) A61K 31/4985 (2006.01)
Patent
CA 2750059
Coated tablets of (6-(5-chloro-2-pyridyl)-5-[(4-methyl-1- piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrro- lo[3,4-b]pyrazine) are provided. The tablets minimize the perceived bitterness of the medicament. A method for analyzing instan-taneous dissolution of sub-microgram quantities of core material is also disclosed.
La présente invention concerne des comprimés de 6-(5-chloro-2-pyridyl)-5-[(4-méthyl-1-pipérazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5h-pyrrolo[3,4-b]pyrazine enrobés. Ces comprimés réduisent fortement la sensation d'amertume que donne le médicament. L'invention concerne également un procédé permettant d'analyser la dissolution instantanée de quantités de matière de noyau inférieures au microgramme.
Bonasia Philip Jr.
Hsia Richard
Huang Cei Gu
Misra Tushar
Saranteas Konstantinos
Gowling Lafleur Henderson Llp
Sunovion Pharmaceuticals Inc.
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