Coated tablets of...

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/28 (2006.01) A61K 31/4985 (2006.01)

Patent

CA 2750059

Coated tablets of (6-(5-chloro-2-pyridyl)-5-[(4-methyl-1- piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrro- lo[3,4-b]pyrazine) are provided. The tablets minimize the perceived bitterness of the medicament. A method for analyzing instan-taneous dissolution of sub-microgram quantities of core material is also disclosed.

La présente invention concerne des comprimés de 6-(5-chloro-2-pyridyl)-5-[(4-méthyl-1-pipérazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5h-pyrrolo[3,4-b]pyrazine enrobés. Ces comprimés réduisent fortement la sensation d'amertume que donne le médicament. L'invention concerne également un procédé permettant d'analyser la dissolution instantanée de quantités de matière de noyau inférieures au microgramme.

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