Coated trimebutine maleate tablet

Details Coated trimebutine maleate tablet Coated trimebutine maleate tablet

A - Human Necessities

61

K

A61K 31/24 (2006.01) A61K 9/28 (2006.01)

Patent

CA 2256751

A coated trimebutine maleate tablet for oral delivery, including a core containing 30-60 % of trimebutine maleate, carriers suitable for preparing said core and carriers enhancing the stability and release of the active principle, as well as a water-soluble coating temporarily but sufficiently effective to prevent disintegration of the core and premature release of the active principle in the mouth.

Comprimé pelliculé de maléate de trimébutine destiné à l'administration par voie orale, caractérisé en ce qu'il comprend: un noyau comprenant de 30 à 60 % de maléate de trimébutine, et des excipients adaptés à la préparation dudit noyau et ceux appropriés à la stabilité et à la libération du principe actif, un pelliculage hydrosoluble, d'efficacité transitoire mais suffisante pour préserver d'une désintégration du noyau et d'une libération prématurée du principe actif en milieu buccal.

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