Coated veterinary implant comprising melatonin

A - Human Necessities – 61 – K

Patent

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167/164, 167/240

A61K 9/36 (2006.01) A61D 7/00 (2006.01) A61K 9/00 (2006.01) A61K 9/22 (2006.01) A61K 31/40 (2006.01) A61K 31/405 (2006.01)

Patent

CA 1334000

A coated veterinary implant including (a) a veterinary implant including an effective amount of (i) an active ingredient selected from melatonin or related chemicals of the indole class, as hereinafter defined, or mixtures thereof, and (ii) a veterinarily acceptable carrier or excipient, and (b) a coating for said veterinary implant (a) formed from a physiologically compatible polymeric coating composition; which implant, in use, releases the active ingredient at a rate sufficient to maintain the blood level of melatonin or related chemicals of the indole class at or above a level sufficient, and for a period sufficient, to regulate seasonal breeding activity and/or seasonal physiological responses of an animal to be treated.

586124

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