A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 33/00 (2006.01)
Patent
CA 2218103
The coating consists of a composition, the components of which are soluble in a solvent, preferably chloroform. In detail, they are a medicament carrier like poly-D, L-lactide, serine protease inhibitors, advantageously thrombin inhibitors and prostaglandines or prostacyclines or derivatives thereof. With such a coating, coated bio-material in the tissue or in the bloodstream are continuously slowly decomposed and the formation of thromboses is prevented.
L'invention concerne un revêtement contenant une composition dont les constituants sont solubles dans un solvant, de préférence dans le chloroforme. Cette composition comprend un excipient de médicament, par exemple poly-D, L-lactide, des inhibiteurs de la sérine protéase, de préférence des inhibiteurs de la thrombine, ainsi que de la prostaglandine ou de la prostacycline ou leurs dérivés. Ce revêtement permet à la matière biologique revêtue de se décomposer lentement dans le tissu ou le flux sanguin et d'empêcher la formation de thromboses.
Alt Eckhard
Reers Martin
Stemberger Axel
Stuber Werner
Behringwerke Aktiengesellschaft
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Hoechst Aktiengesellschaft
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