Coating material for solid medicine and solid medicine...

A - Human Necessities – 61 – K

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Details

A61K 47/32 (2006.01) A61K 9/34 (2006.01) A61K 47/14 (2006.01) A61K 47/46 (2006.01)

Patent

CA 2744008

An object of the present invention is to provide a coating material for a solid formulation which is capable of stably retaining the effective ingredient in the solid formulation for a prolonged period even in unpacked condition in such a manner that the solid formulation can be used in a single-dose formulation. The present invention provides a coating material for a solid formulation which comprises a high hydrogen-bonding resin and a swelling clay and, when coated on a solid formulation and dried, forms a coating film in which the laminated structures of the aforementioned swelling clay are oriented planarly and dispersed in a network fashion.

Cette invention se rapporte à un matériau de revêtement de médicaments solides qui est capable de contenir de manière stable la substance active d'un médicament solide aussi longtemps que le médicament solide, même dans un état déballé, peut être placé dans un emballage unidose. Le matériau de revêtement de médicaments solides comprend une résine qui présente une tendance élevée de liaison hydrogène et une argile gonflante. Lorsque le matériau de revêtement est appliqué à un médicament solide et séché, se forme un film de revêtement dans lequel les structures lamellaires de l'argile colloïdale ont été orientées selon un agencement plan et dispersées dans un état de réseau.

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