Coating suspensions (comprising osmopolymers, osmagents) for...

C - Chemistry – Metallurgy – 09 – D

Patent

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C09D 101/02 (2006.01) A61K 9/00 (2006.01) A61K 9/54 (2006.01) A61K 31/085 (2006.01) C09D 129/04 (2006.01)

Patent

CA 2490683

The present invention includes an expandable osmotic layer and a coating suspension for providing an expandable osmotic layer, both of which are useful for the manufacture of controlled release dosage forms. The expandable osmotic layer of the present invention may be produced using the coating suspension of the present invention. Advantageously, the coating suspension of the present invention can be used to coat expandable osmotic layers under both wet and dry process conditions without sacrificing the quality of the expandable osmotic layers produced, and therefore provides a relatively robust coating suspension that facilitates commercial production of controlled release dosage forms including a coated expandable osmotic layer.

La présente invention concerne une couche osmotique expansible et une suspension de revêtement permettant de réaliser une couche osmotique expansible, l'une et l'autre convenant à la fabrication de formes posologiques à libération contrôlée. La suspension de la présente invention convient particulièrement à la production de la couche osmotique expansible de la présente invention. En l'occurrence, la suspension de revêtement de la présente invention convient particulièrement à l'application de couches osmotiques expansibles par procédés secs ou humides, sans inconvénient pour la qualité des couches osmotiques expansibles produites. On obtient ainsi une suspension de revêtement tenant relativement bien et se prêtant bien à la production commerciale de doses posologiques à libération contrôlée sur lesquelles a été appliquée une couche osmotique expansible.

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