C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 9/00 (2006.01) A61K 31/295 (2006.01) A61K 31/70 (2006.01) A61K 31/7088 (2006.01) A61K 38/00 (2006.01) A61K 38/43 (2006.01) C07C 251/12 (2006.01) C07C 251/16 (2006.01) C07F 15/06 (2006.01) C07H 21/00 (2006.01) C07H 23/00 (2006.01) C07K 1/113 (2006.01) C07K 5/00 (2006.01) C07K 7/00 (2006.01) C07K 14/00 (2006.01) C12N 9/99 (2006.01)
Patent
CA 2207748
The present invention is directed to cobalt compounds that can exchange or bind functional moieties such as histidine on a protein's surface resulting in the inactivation of a biological activity of the protein due to the complexing of the functional moiety to the cobalt compound.
La présente invention concerne des composés de cobalt pouvant assurer l'échange ou la liaison de fractions fonctionnelles telles que l'histidine sur une surface de protéine, ce qui entraîne l'inhibition d'une activité biologique de la protéine par des complexes de fraction fonctionnelle pour les composés en question.
Gray Harry B.
Meade Thomas J.
Takeuchi Toshihiko
California Institute Of Technology
Smart & Biggar
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