Cocaine receptor binding ligands

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 471/18 (2006.01) A61K 31/46 (2006.01) C07D 401/04 (2006.01) C07D 413/04 (2006.01) C07D 451/02 (2006.01)

Patent

CA 2333086

The invention relates to novel compounds which show high affinity for cocaine receptors in the brain, particularly dopamine and serotonin transporter sites. The compounds may be used as imaging or pharmaceutical agents, in the diagnosis and treatment of drug addiction, depression, anorexia and neurodegenerative diseases.

L'invention concerne de nouveaux composés présentant une forte affinité pour les récepteurs de la cocaïne dans le cerveau, en particulier pour les sites transporteurs de dopamine et de sérotonine. Ces composés peuvent être utilisés comme agents de visualisation ou comme agents pharmaceutiques pour le diagnostic et le traitement de la toxicomanie, de la dépression, de l'anorexie et des maladies neurodégénératives.

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