Cochleate delivery vehicles

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/44 (2006.01) A23L 1/22 (2006.01) A23L 1/29 (2006.01) A23P 1/04 (2006.01) A61K 9/10 (2006.01) A61K 9/127 (2006.01) A61K 38/28 (2006.01) A61K 39/145 (2006.01) A61K 45/00 (2006.01)

Patent

CA 2246754

The instant disclosure relates to cochleates comprising a) a biologically relevant molecule component, b) a negatively charged lipid component, and c) a divalent cation component. The cochleate has an extended shelf life, even in a desiccated state. Advantageously, the cochleate can be ingested. The biologically relevant molecule can be a polynucleotide or a polypeptide.

La présente invention se rapporte à des structures cochléaires comportant (a) un composant moléculaire biologiquement utile, (b) un composant lipidique négativement chargé et (c) un composant cationique divalent. Ladite structure cochléaire a une durée de conservation prolongée, même sous sa forme déshydratée. Elle peut être avantageusement ingérée. La molécule biologiquement utile peut être un polynucléotide ou un polypeptide.

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