Codon optimized dna sequence for insect toxin aait

Details Codon optimized dna sequence for insect toxin aait Codon optimized dna sequence for insect toxin aait

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01N 63/00 (2006.01) A01N 63/02 (2006.01) C07K 14/435 (2006.01) C12N 5/10 (2006.01) C12N 7/01 (2006.01) C12N 15/866 (2006.01)

Patent

CA 2113981

CODON OPTIMIZED DNA SEQUENCE FOR INSECT TOXIN AaIT Abstract of the Disclosure This invention provides for the construction of a codon optimized DNA sequence encoding the insect-specific toxin Androctonus australis insect toxin (AaIT). The codon optimized sequence is then inserted into an insect virus. A susceptible insect which ingests such a modified insect virus will cease feeding on plants due to a toxin-induced paralysis at an earlier time than an insect which ingests a wild-type insect virus lacking an AaIT gene.

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