Collagen-based adhesives, methods of preparation and...

C - Chemistry – Metallurgy – 08 – H

Patent

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C08H 1/00 (2006.01) A61L 24/10 (2006.01) C08H 1/06 (2006.01) C09J 189/06 (2006.01) A61F 9/008 (2006.01) A61L 25/00 (1990.01)

Patent

CA 2101637

Collagen-based compositions as adhesives and sealants for medical use and preparation thereof are described. Prior to po- lymerization, soluble or partially fibrillar collagen monomers in solution are chemically modified with an acylating agent, sulfo- nating agent or a combination of the foregoing. The collagen compositions prepared accordingly can be used as medical adhe- sives for bonding soft tissues or be made in to a sealant film for a variety of medical uses such as wound closures and tendon wraps for preventing adhesion formation following surgery.

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