Collagen implants having improved tensile properties

Details Collagen implants having improved tensile properties Collagen implants having improved tensile properties

A - Human Necessities

61

L

A61L 27/00 (2006.01) A61L 27/24 (2006.01) A61F 2/00 (2006.01)

Patent

CA 2142209

Collagen-based implants, e.g. cartilage implants, having improved tensile strength, elongation and flexibility are disclosed. The implants are prepared by forming a mixture of an atelopeptide collagen fiber and a crosslinking agent, forming the mixture into a gelled shaped article, drying the gelled shaped article under controlled drying conditions to a moisture level of 30 to 40% by weight, and curing the dried article under controlled curing conditions to a moisture level of less than 30% by weight. The drying and curing conditions give rise to tightly crosslinked, rehydratable implants having an equilibrium hydration value of less than 350% by weight.

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