Collagen peptide composition having good ability to enter...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 4/12 (2006.01) A23L 1/305 (2006.01) A61K 38/17 (2006.01) A61P 3/02 (2006.01) A61P 17/16 (2006.01) A61P 19/10 (2006.01) C07K 14/78 (2006.01) C07K 1/12 (2006.01)

Patent

CA 2759424

The purpose of the present invention is to find out collagen peptides effective for transferring di- or tripeptides, which serve as the active components of collagen, into the blood to thereby reduce the required intake thereof. Disclosed is a collagen peptide composition obtained by digesting collagen or gelatin with protease, characterized in that: (a) the ratio of hydroxyproline in the amino acid residues at the second position from the N-terminus of the peptides contained in the composition is 2 to 20 mol% inclusive, and the ratio of glycine in the amino acid residues at the third position from the N-terminus thereof is 20 to 50 mol% inclusive; and (b) the average molecular weight of the composition is 500 to 2000 inclusive.

Le but de la présente invention est de découvrir des peptides de collagène efficaces pour transférer des di- ou des tripeptides, qui servent comme composants actifs du collagène, à l'intérieur du sang pour réduire de ce fait l'apport nécessaire. L'invention concerne une composition peptidique de collagène obtenue en faisant digérer le collagène ou la gélatine par une protéase, caractérisée en ce que : (a) la proportion d'hydroxyproline dans les résidus acides aminés en seconde position à partir de l'extrémité N-terminale des peptides contenus dans la composition est de 2 à 20 % en moles inclus, et la proportion de glycine dans les résidus acides aminés en troisième position à partir de l'extrémité N-terminale de ceux-ci est de 20 à 50 % en moles inclus ; et (b) le poids moléculaire moyen de la composition est de 500 à 2 000 inclus.

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