Collagen scaffolds, medical implants with same and methods...

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/00 (2006.01) A61B 5/145 (2006.01) A61K 9/22 (2006.01) A61K 38/39 (2006.01)

Patent

CA 2656044

The subject invention concerns non-degradable three dimensional porous collagen scaffolds and coatings. These scaffolds can be prepared around sensors for implantation into a body. A specific embodiment of the invention concerns implantable glucose sensors. Sensors comprising a collagen scaffold of the invention have improved biocompatibility by minimizing tissue reactions while stimulating angiogenesis. The subject invention also concerns methods for preparing collagen scaffolds of the invention. The subject invention also concerns sensors that have a collagen scaffold of the invention around the exterior of the sensor.

L'invention concerne des échafaudages et des revêtements de collagène poreux tridimensionnels non dégradables. Ces échafaudages peuvent être préparés autour de capteurs pour une implantation dans un corps. Un mode de réalisation précis de l'invention concerne des capteurs de glucose implantables. Des capteurs comportant l'échafaudage de collagène de l'invention ont amélioré la biocompatibilité en réduisant au minimum des réactions de tissu tout en stimulant l'angiogenèse. L'invention concerne également des procédés pour préparer les échafaudages de collagène de l'invention. L'invention concerne aussi des capteurs qui ont l'échafaudage de collagène de l'invention autour de l'extérieur du capteur.

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