Collagen-thrombin compositions

Details Collagen-thrombin compositions Collagen-thrombin compositions

A - Human Necessities

61

L

167/104

A61L 15/64 (2006.01) A61L 15/32 (2006.01) A61L 15/42 (2006.01) C08L 89/06 (2006.01)

Patent

CA 1217135

COLLAGEN-THROMBIN COMPOSITIONS ABSTRACT OF THE DISCLOSURE A method of forming a collagen-thrombin hemostatic composition is comprised of forming a homogeneous aqueous ad- mixture of collagen and thrombin at a basic pH and lyophilizing the collagen-thrombin admixture to form a stable collagen sponge having thrombin therein. The collagen utilized in the process is absorbable when placed in vivo. Additionally, a lyophilized collagen product is comprised of collagen which is absorbable when placed in vivo and thrombin distributed within the collagen. The collagen product is storage stable.

463320

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