Collapsin response mediator protein-1

Details Collapsin response mediator protein-1 Collapsin response mediator protein-1

C - Chemistry, Metallurgy

07

K

C07K 16/18 (2006.01) A61K 38/16 (2006.01) A61K 47/48 (2006.01) A61P 35/04 (2006.01) C07K 14/47 (2006.01) C07K 16/28 (2006.01) C07K 16/30 (2006.01) C12Q 1/68 (2006.01) G01N 33/554 (2006.01) G01N 33/566 (2006.01) G01N 33/574 (2006.01) C12N 5/08 (2006.01)

Patent

CA 2391568

This invention is based on the discovery of an association of Collapsin Response Mediator Protein-1 (CRMP-1) with tumor metastasis. The level of CRMP- 1 protein or mRNA can be used as an indicator of cellular invasiveness and of a test compound's ability to alter cellular invasiveness. The level of CRMP-1 protein can also be altered, e.g., to reduce invasiveness.

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