Collection of prokaryotic dna for two hybrid systems...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/10 (2006.01) A61K 39/106 (2006.01) A61K 39/40 (2006.01) A61K 48/00 (2006.01) C07K 14/205 (2006.01) C07K 16/12 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 15/31 (2006.01) C12N 15/86 (2006.01) C12Q 1/68 (2006.01) G06F 17/00 (2006.01)

Patent

CA 2371596

The present invention concerns collections of recombinant cell clones derived from a prokaryotic genome, more particularly from Helicobacter pylori genome, usable for two-hybrid systems and methods to produce such collections. The invention further relates to the identification of H. pylori protein-protein interactions and to the application of said collections of recombinant cell clones and said identified proteins interactions to the pharmaceutical and diagnostic field.

La présente invention concerne des collections de clones de cellule de recombinaison dérivés d'un génome procaryote, plus particulièrement d'un génome d'Helicobacter pylori, utilisables pour deux systèmes hybrides, et des techniques permettant de produire ces collections. Cette invention a trait aussi à l'identification des interactions protéine-protéine et à l'application de ces collections de clones de cellule de recombinaison et de ces interactions de protéines identifiées dans le domaine pharmaceutique et celui du diagnostic.

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