G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/58 (2006.01) C07K 1/13 (2006.01) G01N 33/543 (2006.01) G01N 33/566 (2006.01)
Patent
CA 2569553
The invention concerns the use of a collection of traceable cationic compounds for determining ligands of a receptor whose ligand is unknown or whose ligand useful for specific affinity binding studies is unknown, said traceable cationic compounds being characterized in that they comprise at least one basic amino acid residue providing the cationic type to said compound and a tracer group, in particular a fluorophor, a colouring agent or a quencher.
La présente invention concerne l'utilisation d'une collection de composés traçables de type cationique, pour la détermination de ligands d'un récepteur dont on ne connaît pas de ligand ou dont on ne connaît pas de ligand utilisable pour les études de liaison d'affinité spécifique, lesdits composés traçables de type cationique étant caractérisés en ce qu'ils comprennent au moins un résidu d'acide aminé à caractère basique conférant le type cationique audit composé et un groupement traceur, notamment un fluorophore, un colorant ou un "quencher".
Franchet Christel Anne
Galzi Jean-Luc
Guillier Fabrice Yves
Hibert Marcel Francois Louis
Pattus Franc Emile Jean
Centre National de La Recherche Scientifique
Goudreau Gage Dubuc
Universite Louis Pasteur de Strasbourg
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