C - Chemistry – Metallurgy – 08 – G
Patent
C - Chemistry, Metallurgy
08
G
C08G 69/26 (2006.01) A61K 9/10 (2006.01) A61K 9/51 (2006.01) A61K 47/34 (2006.01) B01J 13/00 (2006.01) C08G 69/28 (2006.01)
Patent
CA 2482932
The invention concerns a suspension of particles for delivering active principles, in particular proteins. Said particles are based on a diblock copolymer consisting of a neutral hydrophobic alpha hydroxy carboxylic acid polymer block and a hydrophilic linear polyaminoacid block with peptide alpha chaining, at least partly ionized. Said alpha hydroxy carboxylic acid polymer/ linear polyaminoacid delivery particles spontaneously obtainable in the absence of surfactant can be stable. Said delivery particles are capable of being associated undissolved in colloidal suspension with at least an active principle and of delayed or prolonged release thereof. The invention also concerns a powdery solid from which are derived the delivery particles and the preparation of said solid and said delivery particle suspension.
L'invention concerne une suspension de particules de vectorisation (PV) de principes actifs (PA) en particulier de protéines. Ces PV sont à base d'un copolymère dibloc formé d'un bloc de Polymère d'Acide Alpha HydroxyCarboxylique (PAHC) neutre hydrophobe et d'un bloc de polyaminoacide(s) linéaire(s) hydrophile(s) à enchainement alpha peptidique polyAAI, ionisés au moins en partie. Ces PV PAHC/polyAAI peuvent être obtenues spontanément en l'absence de tensioactif et être stables. Ces PV sont aptes à s'associer en suspension colloidale à l'état non dissous avec au moins un PA et à libérer celui ci de facon retardée ou prolongée. . L'invention vise également un solide pulvérulent à partir duquel sont issues les PV, ainsi que la préparation de ce solide et de cette suspension de PV.
Bryson Nathan
Caillol Sylvain
Meyrueix Remi
Mingotaud Anne-Francoise
Soula Gerard
Flamel Technologies
Robic
LandOfFree
Colloidal suspension of submicronic particles for delivering... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Colloidal suspension of submicronic particles for delivering..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Colloidal suspension of submicronic particles for delivering... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2029922