Colon cancer kh-1 and n3 antigens

Details Colon cancer kh-1 and n3 antigens Colon cancer kh-1 and n3 antigens

C - Chemistry, Metallurgy

08

B

C08B 37/00 (2006.01) A61K 31/15 (2006.01) A61K 47/48 (2006.01) C07H 15/10 (2006.01)

Patent

CA 2277867

The present invention provides processes for the preparation of the KH-1 and N3 antigens, as well as related analogues thereof, which are useful as anticancer therapeutics. The present invention also provides various intermediates useful in the preparation of KH-1 and N3 and analogues thereof. Additionally, the invention provides various compositions comprising any of the analogues of KH-1 and N3 available through the methods of the invention and pharmaceutical carriers useful in the treatment of subjects suffering from various forms of epithelial cancer.

La présente invention concerne des procédés de préparation d'antigènes KH-1 et N3, et de leurs analogues associés, qui sont utiles comme substances thérapeutiques contre le cancer. La présente invention concerne également divers produits intermédiaires utiles pour la préparation de KH-1 et de N3 et de leurs analogues. De plus, l'invention a trait à diverses compositions renfermant tout analogue de KH-1 et de N3 obtenu selon les procédés décrits dans l'invention, et à des vecteurs pharmaceutiques utiles dans le traitement de sujets atteints de diverses formes de cancer épithélial.

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