Colon cancer related gene tom34

G - Physics – 01 – N

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G01N 33/574 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2616497

Objective methods for detecting and diagnosing colon cancer are described herein. In one embodiment, the diagnostic method involves determining the expression level of TOM34 that discriminates between colon cancer cells and normal cells. Finally, the present invention provides methods of screening for therapeutic agents useful in the treatment of colon cancer, methods of treating colon cancer and method for vaccinating a subject against colon cancer.

La présente invention a trait à des procédés objectifs pour la détection et le diagnostic du cancer du côlon. Dans un mode de réalisation, le procédé de diagnostic comprend la détermination du niveau d'expression de TOM34 qui distingue des cellules du cancer du côlon des cellules normales. L'invention a trait enfin à des procédés de criblage pour des agents thérapeutiques utiles dans le traitement du cancer du côlon, à des procédés de traitement du cancer du côlon et à un procédé pour la vaccination d'un sujet contre le cancer du côlon.

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