Colon crypt cell mitogen, cell line producing it, and uses...

C - Chemistry – Metallurgy – 12 – N

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C12N 5/00 (2006.01) A61K 38/33 (2006.01) A61K 47/48 (2006.01) C07K 14/665 (2006.01) C07K 16/26 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01) C12P 21/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2132095

2132095 9319165 PCTABS00025 The invention describes a colonic crypt cell stimulating mitogen, and conditioned medium containing it. In particular, cell line LIM 2537 is described which, when cultivated in medium, secretes a mitogen which stimulates the proliferation of colonic crypt cells. Applications of the conditioned medium and the cell line are also described.

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