A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/20 (2006.01) A61K 31/765 (2006.01) A61K 33/42 (2006.01) A61P 1/10 (2006.01)
Patent
CA 2546637
This invention relates to novel colonic purgative compositions in a solid dosage form, comprising at least one purgative and at least one soluble, or soluble, nonfermentable binder, such as polyethylene glycol. Further, this invention relates to methods of using the colonic purgative compositions. The present compositions and methods are designed to improve patient tolerance and compliance, while at the same time improving the quality of bowel cleansing. The formulations and methods of this invention are particularly useful to cleanse the bowel prior to diagnostic and surgical procedures and can also be employed in lower dosages as a laxative to promote elimination and/or to relieve constipation.
L'invention concerne des compositions purgatives pour le colon, en forme pharmaceutique solide, qui comprennent au moins un agent purgatif et au moins un agent de liaison soluble, ou soluble non fermentable, du type polyéthylèneglycol. L'invention concerne également des procédés d'utilisation correspondants. Les compositions et les procédés en question visent à améliorer la tolérance du patient et l'observation médicamenteuse, et aussi la qualité du nettoyage intestinal. Ces compositions et ces procédés sont utiles en particulier pour nettoyer les intestins avant des procédures diagnostiques et chirurgicales, et on peut aussi utiliser de tels moyens, selon des doses inférieures, comme laxatifs visant à améliorer l'élimination et/ou à soulager la constipation.
Do Ngoc
Rose Martin
Skiendzielewski Stephen
Inkine Pharmaceutical Company Inc.
Salix Pharmaceuticals Inc.
Smart & Biggar
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