Color-encoding and in-situ interrogation of matrix-coupled...

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/00 (2006.01) B01J 19/00 (2006.01) C07B 61/00 (2006.01) C12Q 1/68 (2006.01) G01N 21/00 (2006.01) G01N 21/76 (2006.01) G01N 33/53 (2006.01) G01N 33/533 (2006.01) G01N 33/543 (2006.01) G01N 33/566 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2291853

A method and apparatus for the physico-chemical encoding of a collection of beaded resin ("beads") to determine the chemical identity of bead-anchored compounds by in-situ interrogation of individual beads. The present invention provides method and apparatus to implement color-coding strategies in applications and including the ultrahigh-throughput screening of bead-based combinatorial compounds libraries as well as multiplexed diagnostic and environmental testing and other biochemical assays.

La présente invention concerne un procédé et un appareil qui permettent le codage physico-chimique d'un ensemble de billes de résine dans le but de déterminer l'identité chimique des composés fixés dans la bille en interrogeant in-situ des billes individuelles. La présente invention se rapporte à un procédé et un appareil permettant de mettre en oeuvre des stratégies de codage couleur dans des applications, y compris un criblage à débit extrêmement élevé de bibliothèques combinatoires de composés fixés dans des billes, ainsi que des tests diagnostiques et environnementaux multiplexés et autres tests biochimiques.

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