C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 498/08 (2006.01) C09B 23/14 (2006.01) C09B 29/36 (2006.01) C09B 53/00 (2006.01) G01N 33/52 (2006.01) G01N 33/84 (2006.01)
Patent
CA 2050394
A chromogenic cryptand found to be especially selective in the determination of lithium in blood of the general formula (I): Image (I) where: n = 1 or 2, R1 and R2, same or different, are hydrogen, lower alkyl, lower alkenyl, or lower alkylidene; and Q is a chromogenic moiety capable of providing a detectable response upon complexation of said compound with lithium ion and has the structure: Image wherein: X is CH, C-OH or N; and Z is p-nitrophenylazo, 2,4-dinitrophenylazo, 2,4,6-trinitrophenylazo, p-nitrostyryl, p-benzoquinonemonoimino, bis-(4-dimethylaminophenyl) hydroxymethyl, 3-phenylisothiazolyl-5-azo, thiazolyl-5-azo; or isothiazolyl-5-azo.
Chapoteau Eddy
Czech Bronislaw P.
Kumar Anand
Macrae & Co.
Technicon Instruments Corporation
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