Combination adjuvant formulation

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 7/08 (2006.01) A61K 39/10 (2006.01) A61K 39/155 (2006.01) A61K 39/39 (2006.01) A61P 31/04 (2006.01) A61P 31/12 (2006.01) A61P 37/04 (2006.01)

Patent

CA 2737352

Methods and compositions for enhancing an immune response to a selected antigen are described. The methods are useful for the treatment and prevention of microbial infections, such as infections caused by bacteria, viruses, fungi and parasites. The methods and compositions include host defense peptides, polyphosphazenes and immunostimulatory sequences to enhance the immune response to a coadministered antigen.

Linvention concerne des procédés et des compositions pour améliorer une réponse immunitaire à un antigène sélectionné. Les procédés sont utiles pour le traitement et la prévention dinfections microbiennes, telles que des infections causées par des bactéries, des virus, des champignons et des parasites. Les procédés et les compositions comprennent des peptides de défense de lhôte, des polyphosphazènes et des séquences immunostimulatrices pour améliorer la réponse immunitaire à un antigène co-administré.

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