Combination agent

Details Combination agent Combination agent

A - Human Necessities

61

K

A61K 45/06 (2006.01) A61K 31/4439 (2006.01) A61K 31/4545 (2006.01) A61K 31/497 (2006.01) A61K 31/506 (2006.01) A61K 31/5377 (2006.01) A61P 1/04 (2006.01) A61P 1/16 (2006.01) A61P 3/10 (2006.01) A61P 7/06 (2006.01) A61P 9/02 (2006.01) A61P 9/04 (2006.01) A61P 9/10 (2006.01) A61P 11/00 (2006.01) A61P 11/06 (2006.01) A61P 13/12 (2006.01) A61P 17/04 (2006.01) A61P 17/06 (2006.01) A61P 19/02 (2006.01) A61P 19/10 (2006.01) A61P 21/00 (2006.01) A61P 25/00 (2006.01) A61P 25/16 (2006.01) A61P 25/28 (2006.01) A61P 29

Patent

CA 2436739

Drugs comprising a combination of one or more p38MAP kinase inhibitors and/or TNF-a production inhibitors with one or more agents selected from the group consisting of: (1) nonsteroidal anti-inflammatory agents; (2) disease- modification antirheumatics; (3) anti-cytokine drugs; (4) immunomodulators; (5) steroidal drugs; and (6) c-JUN N-terminal kinase inhibitors. These concomitant drugs are useful as preventives and remedies for diseases such as rheumatism and arthritis and other diseases.

L'invention concerne des médicaments contenant une combinaison d'un ou de plusieurs inhibiteurs de MAP kinase P38 et/ou d'inhibiteurs de la production de TNF- alpha et d'un ou de plusieurs agents choisis dans le groupe comprenant: (1) des agents anti-inflammatoires non-stéroïdiens; (2) des agents antirhumatismaux modificateurs de la maladie; (3) des médicaments anti-cytokine; (4) des immunomodulateurs; (5) des médicaments stéroïdiens; et (6) des inhibiteurs de kinases c-jun N-terminal. Ces co-prescriptions sont utilisées pour prévenir ou traiter des maladies, telles que le rhumatisme et l'arthrite, ainsi que diverses autres maladies.

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