Combination antiemetic therapy using nk-1 receptor antagonists

Details Combination antiemetic therapy using nk-1 receptor antagonists Combination antiemetic therapy using nk-1 receptor antagonists

A - Human Necessities

61

K

A61K 31/56 (2006.01) A61K 31/44 (2006.01) A61K 31/445 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2188227

The present invention relates to pharmaceutical compositions for treating or preventing emesis in mammals, including humans, using an NK-1 antagonist in combination with one or more other active agents selected from (a) a glucocorticoid or corticosteroid, (b) a benzodiazepine, (c) metaclopramide and (d) an intracellular molecular scavenger. The combination has a synergistic antiemetic effect.

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