Combination between an isothiocyanate and levodopa for...

A - Human Necessities – 61 – K

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A61K 31/198 (2006.01) A61K 31/26 (2006.01) A61K 36/31 (2006.01) A61P 25/16 (2006.01)

Patent

CA 2709524

A combination between levodopa and an extract derived from a vegetable of the Cruciferae family or Brassica genus, this extract containing sulforaphane (4-(methylsulfmyl)butyl isothiocyanate), is disclosed. This combination is useful for the treatment of Parkinson's disease and in particular, for on-off and wearing-off episodes.

La présente invention concerne une combinaison entre le lévodopa et un extrait dérivé d'un légume de la famille des crucifères ou du genre Brassica, cet extrait contenant du sulforaphane (isothiocyanate de 4-(méthylsulfamyl)butyle). Cette combinaison est utile pour le traitement de la maladie de Parkinson et en particulier, pour des épisodes on-off et de wearing-off (akinésie de fin de dose).

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