Combination compositions containing benazepril or...

Details Combination compositions containing benazepril or... Combination compositions containing benazepril or...

A - Human Necessities

61

K

A61K 31/55 (2006.01) A61K 31/41 (2006.01) A61K 38/55 (2006.01)

Patent

CA 2214143

The invention relates to pharmaceutical combination compositions for the treatment of hypertension, congestive heart failure and renal failure, comprising (1) the ACE-inhibitor benazepril of formula (I) or benazeprilat of formula (II) or a pharmaceutically acceptable salt thereof, and (2) the AT1- antagonist valsartan of formula (III) or a pharmaceutically acceptable salt thereof, as weel as to methods for the treatment of hypertension, congestive heart failure and renal failure.

L'invention se rapporte à des compositions de combinaison pharmaceutique pour le traitement de l'hypertension, l'insuffisante cardiaque globale et l'insuffisance rénale, comportant (1) le bénazéprile inhibiteur de ACE de formule (I) ou le bénazéprilat de formule (II) ou un de leurs sels pharmaceutiquement acceptables, et la valsartane antagoniste AT¿1? de formule (III) ou un de leurs sels pharmaceutiquement acceptables, ainsi que les méthodes de traitement de l'hypertension, de l'insuffisance cardiaque globale et de l'insuffisance rénale.

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