Combination comprising a bcrp inhibitor and...

A - Human Necessities – 61 – K

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A61K 31/506 (2006.01)

Patent

CA 2569479

The present invention relates to a combination which comprises a BCRP inhibitor and Compound I of formula (I), in which the active ingredients are present in each case in free form or in the form of a pharmaceutically acceptable salt and optionally at least one pharmaceutically acceptable carrier for simultaneous, separate or sequential use, especially in the delay of progression or treatment of cancer, and to pharmaceutical compositions comprising such combinations.

La présente invention concerne une combinaison qui comprend un inhibiteur BCRP et un composé I représenté par la formule (I), dans laquelle les principes actifs sont présents dans chaque cas sous une forme libre ou sous forme de sel répondant aux normes pharmaceutiques et, éventuellement, au moins un porteur répondant aux normes pharmaceutiques pour une utilisation simultanée séparée ou séquentielle, en particulier dans le délai de la progression d'un cancer ou du traitement d'un cancer et, des compositions pharmaceutiques comprenant ces combinaisons.

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