Combination comprising a cdk inhibitor and cisplatin

Details Combination comprising a cdk inhibitor and cisplatin Combination comprising a cdk inhibitor and cisplatin

A - Human Necessities

61

K

A61K 33/24 (2006.01) A61K 31/282 (2006.01) A61K 31/52 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2502969

A first aspect of the invention relates to a combination comprising a CDK inhibitor and cisplatin. A second aspect of the invention relates to a pharmaceutical product comprising a CDK inhibitor and cisplatin as a combined preparation for simultaneous, sequential or separate use in therapy. A third aspect of the invention relates to a method of treating a proliferative disorder, said method comprising simultaneously, sequentially or separately administering a CDK inhibitor and cisplatin to a subject.

Dans un premier mode de réalisation, l'invention concerne une combinaison comprenant un inhibiteur de CDK et du cisplatine. Dans un deuxième mode de réalisation, l'invention concerne un produit pharmaceutique contenant un inhibiteur de CDK et du cisplatine en tant que préparation combinée pour utilisation simultanée, séquentielle ou séparée en thérapie. Dans un troisième mode de réalisation l'invention concerne un procédé de traitement d'un trouble prolifératif, ce procédé consistant à administrer simultanément, séquentiellement ou séparément à un sujet un inhibiteur de CDK et du cisplatine.

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