Combination comprising a vasculostatic compound and an...

A - Human Necessities – 61 – K

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Details

A61K 31/495 (2006.01) A61K 31/17 (2006.01) A61K 31/4188 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2490130

The invention relates to pharmaceutical combination which comprises (a) a vasculostatic compound, (b) an alkylating agent and (c) optionally at least one pharmaceutically acceptable carrier to simultaneous, separate or sequential use for the treatment of a tumor disease; a pharmaceutical composition comprising such a combination; the use of such a combination for the preparation of a medicament for the treatment of a tumor disease; a commercial package or product comprising such a combination as a combined preparation for simultaneous, separate or sequential use, and to a method of treatment of a warm-blooded animal, especially a human.

L'invention concerne une combinaison pharmaceutique contenant (a) un composé vasculostatique, (b) un agent d'alkylation et (c) éventuellement au moins un excipient pharmaceutiquement compatible destinés à une utilisation simultanée, séparée ou séquentielle aux fins de traitement d'une maladie tumorale. L'invention concerne également une composition pharmaceutique contenant une telle combinaison; l'utilisation d'une telle combinaison pour préparer un médicament destiné au traitement d'une maladie tumorale; un emballage ou produit commercial comprenant une telle combinaison comme une préparation combinée destinée à une utilisation simultanée, séparée or séquentielle et un procédé de traitement d'un animal à sang chaud, notamment d'un être humain.

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