A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/216 (2006.01) A61K 9/08 (2006.01) A61K 9/10 (2006.01) A61K 9/12 (2006.01) A61K 31/402 (2006.01) A61K 31/42 (2006.01) A61K 31/436 (2006.01) A61K 31/445 (2006.01) A61K 31/4465 (2006.01) A61K 31/4545 (2006.01) A61K 38/08 (2006.01) A61K 38/55 (2006.01) A61K 39/395 (2006.01) A61K 47/30 (2006.01) A61P 17/02 (2006.01) A61P 41/00 (2006.01)
Patent
CA 2638747
The present invention describes various devices and methods wherein a cytostatic antiproliferative drug, either alone or in combination with other drugs, is placed between internal body tissues to prevent the formation of scar tissue and/or adhesions during healing of a wound or surgical site. Specific devices to achieve this administration include, but are not limited to, a permanent implant or a biodegradable material having an attached antiproliferative drug such as sirolimus. These antiproliferative drugs may be combined with other drugs including, but not limited to, antiplatelets, antithrombotics or anticoagulants. The present invention also contemplates methods to a reduce scar tissue and/or adhesions or adhesion formation at an anastomosis site. In particular, a cytostatic antiproliferative drug is administered to an arteriovenous shunt anastomoses in patients having end- stage renal disease.
Fischell Tim A.
Luderer Jack R.
Shebuski Ronald J.
Afmedica Inc.
Smart & Biggar
LandOfFree
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