A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/58 (2006.01) A61K 45/06 (2006.01)
Patent
CA 2199980
Described is a combination method using selective inhibitors of 5.alpha.- reductase 1 and/or 2 including 7.beta.-substituted 4-aza-5.alpha.-cholestan-3- ones and related 4-aza-5.alpha.-androstan-3-one compounds which are useful in the treatment of acne vulgaris in combination with at least one agent selected from an antibacterial, keratolytic, and/or an anti-inflammatory.
On décrit un procédé combiné consistant à utiliser des inhibiteurs sélectifs de la 5.alpha.-réductase 1 et/ou 2, y compris des 4-aza-5.alpha.-cholestane-3-ones 7.beta.-substitués et des composés apparentés de type 4-aza-5.alpha.-androstane-3-one, qui sont utiles dans le traitement de l'acné vulgaire, en combinaison avec au moins un agent choisi parmi un antibactérien, un kératolytique et/ou un anti-inflammatoire.
Merck & Co. Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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