Combination modality cancer therapy

Details Combination modality cancer therapy Combination modality cancer therapy

A - Human Necessities

61

K

167/119

A61K 31/28 (2006.01) A61K 33/24 (2006.01) C01B 21/50 (2006.01) C01G 55/00 (2006.01) C07F 15/00 (2006.01)

Patent

CA 1254831

ABSTRACT Coordination compounds for use in therapy, the compounds having the general empirical formula: [RhmXxYy]a in which m is the oxidation state of Rh, X is at least one anionic ligand, Y is at least one neutral ligand, with the proviso that at least one of X and Y is a nitrogen donor ligand, x is an integer from 1 to 6, y is an integer from 1 to 5 or may be equal to zero, and a is a positive or negative integer from -3 to +3 or may be equal to zero. Such compounds are useful inter alia as radiosensitisers in the treatment of carrier. A preferred compound is [RhenCl4]2 [enH2].

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