Combination of a bis-thiazolium salt or a precursor thereof...

A - Human Necessities – 61 – K

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Details

A61K 31/427 (2006.01) A61K 31/357 (2006.01) A61K 31/366 (2006.01) A61K 31/37 (2006.01) A61K 31/426 (2006.01) A61K 45/06 (2006.01) A61P 33/06 (2006.01)

Patent

CA 2714184

The invention relates to an association that comprises a salt of bis- thiazolium, a compound of the formula (VI) or a precursor thereof, and artemisinin or a derivative thereof. The invention also relates to a pharmaceutical composition that comprises at least one salt of bis- thiazolium, a compound of the formula (VI) or a precursor thereof, and artemisinin or a derivative thereof. The invention further relates to the use of this combination for preparing a drug for treating or preventing acute malaria. The invention ultimately relates to a kit for treating or preventing acute malaria.

L'invention a pour objet une association, qui comprend un sel de bis- thiazolium, composé de formule (VI) ou l'un de ses précurseurs, et l'artémisinine ou l'un de ses dérivés. L'invention a également pour objet une composition pharmaceutique comprenant au moins un sel de bis-thiazolium, composé de formule (VI) ou l'un de ses précurseurs, et l'artémisinine ou l'un de ses dérivés. L'invention a aussi pour objet l'utilisation d'une telle association pour la préparation d'un médicament destiné au traitement ou à la prévention du paludisme sévère. L'invention a enfin pour objet un kit pour le traitement ou la prévention du paludisme sévère.

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