Combination of a cyclosporine derivative and nucleosides for...

A - Human Necessities – 61 – K

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A61K 31/7068 (2006.01) A61K 38/13 (2006.01) A61P 31/12 (2006.01)

Patent

CA 2748792

This invention relates to combinations comprising 3-[(R)-2-(N,N- dimethylamino)ethylthio-Sar]- 4-(gammahydroxymethylleucine) cyclosporine, or a pharmaceutically acceptable salt, solvate or hydrate thereof; and certain nucleoside analogues, and their use in the treatment of hepatitis C virus.

Cette invention porte sur des combinaisons renfermant de la 3-[(R)-2-(N,N-diméthylamino)éthylthio-Sar]-4-(gammahydroxyméthylleucine)cyclosporine ou un sel, solvate ou hydrate pharmaceutiquement acceptable correspondant, et certains analogues nucléosidiques, et sur l'utilisation de ces combinaisons dans le traitement du virus de l'hépatite C.

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