Combination of a dpp-iv inhibitor and a cannabinoid cb1...

A - Human Necessities – 61 – K

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A61K 31/401 (2006.01) A61K 31/454 (2006.01) A61K 45/06 (2006.01) A61P 3/00 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) A61P 25/30 (2006.01)

Patent

CA 2614834

The present invention relates to a combination, such as a combined preparation or pharmaceutical composition, respectively, comprising of a DPP IV inhibitor or a pharmaceutically acceptable salt thereof and comprising at least one CB1 antagonist, or a pharmaceutically acceptable salt thereof. The present invention furthermore relates to the use of such a combination for the prevention of, delay of progression of, treatment of diseases and disorders that may be inhibited by DPP IV inhibition, appetency disorders or substance abuse disorders.

L'invention concerne une combinaison, telle qu'une préparation combinée ou une composition pharmaceutique, respectivement, constituée d'un inhibiteur de la DPP IV ou d'un sel pharmaceutiquement acceptable de celui-ci et d'au moins un antagoniste des récepteurs CB1 ou d'un sel pharmaceutiquement acceptable de celui/ceux-ci. L'invention concerne de plus l'utilisation de cette combinaison pour prévenir, retarder la progression ou traiter des maladies et des troubles pouvant être inhibés par l'inhibition de la DPP IV, des troubles de l'appétit ou des troubles liés à l'abus d'alcool ou d'autres drogues.

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