Combination of a macrolide and a local anesthetic for the...

Details Combination of a macrolide and a local anesthetic for the... Combination of a macrolide and a local anesthetic for the...

A - Human Necessities

61

K

A61K 31/436 (2006.01) A61K 31/08 (2006.01) A61K 31/167 (2006.01) A61P 17/00 (2006.01)

Patent

CA 2521261

Synergistic combinations of a macrolide T-cell immunomodulator or immunosuppressant such as 33-epichloro-33-desoxyascomycin and a local anaesthetic such as lidocaine, polidocanol or prilocaine are provided, which are useful in particular in the treatment of dermatological diseases such as atopic, contact or seborrhoeic dermatitis, psoriasis, acne, rosacea, post- peel, pruritus, skin burning, or itching; and associated pain.

L'invention porte sur des combinaisons synergiques d'un immunomodulateur ou immunosuppresseur des lymphocytes T d'un macrolide tel que la 33-épichloro-33-désoxyascomycine et d'un anesthésique local tel que la lidocaïne, le polidocanol ou la prilocaïne, qui sont utiles, notamment, dans le traitement de maladies dermatologiques telles que la dermatite atopique, de contact ou séborrhéique, le psoriasis, l'acné, la rosacée, l'après-épilation, le prurit, les brûlures et la douleur associée.

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