A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/14 (2006.01) A61K 31/192 (2006.01) A61K 31/5415 (2006.01) A61P 25/06 (2006.01)
Patent
CA 2723998
A composition of a triptan and particles of a NSAID. The NSAID particles having an effective average particle size of less than 2000 nm and at least one surface stabilizer adsorbed on the surface thereof. The NSAID component of the composition, in a comparative pharmacokinetic testing with a non-particulate NSAID in the same dosage strength and form, exhibits a shorter time to Tmax when compared to the time to Tmax of the non--nanoparticulate NSAID.
La présente invention concerne une composition de tryptan et de particules dAINS. Lesdites particules de lAINS présentent une taille de particule moyenne efficace inférieure à 2000 nm et au moins un stabilisant de surface adsorbé à leur surface. Le composant AINS de la composition, dans une analyse pharmacocinétique comparative avec un AINS non particulaire au même dosage et sous la même forme, présente un temps plus court jusquà Tmax comparativement au temps mis pour atteindre Tmax avec lAINS non nanoparticulaire.
Jenkins Scott
Liversidge Gary
Elan Pharma International Limited
Kirby Eades Gale Baker
LandOfFree
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