Combination of aldose reductase inhibitors and...

Details Combination of aldose reductase inhibitors and... Combination of aldose reductase inhibitors and...

A - Human Necessities

61

K

A61K 31/502 (2006.01) A61K 31/13 (2006.01) A61K 31/16 (2006.01) A61K 31/167 (2006.01) A61K 31/185 (2006.01) A61K 31/198 (2006.01) A61K 31/277 (2006.01) A61K 31/353 (2006.01) A61K 31/4184 (2006.01) A61K 31/4188 (2006.01) A61K 31/426 (2006.01) A61K 31/4422 (2006.01) A61K 31/4747 (2006.01) A61K 31/517 (2006.01) A61K 31/538 (2006.01) A61K 31/554 (2006.01) A61K 45/06 (2006.01) A61K 45/08 (2006.01) A61P 3/10 (2006.01) A61P 9/00 (2006.01) A61P 9/10 (2006.01) A61P 9/12 (2006.01) A61P 13/12 (2006.01) A61P 25/00 (200

Patent

CA 2327575

This invention is directed to methods, pharmaceutical compositions and kits comprising an aldose reductase inhibitor (ARI), a prodrug thereof or a pharmaceutically acceptable salt of said ARI or said prodrug and an antihypertensive agent, a prodrug thereof or a pharmaceutically acceptable salt of said antihypertensive agent or said prodrug. This invention further relates to methods of using those pharmaceutical compositions for the treatment of diabetic complications such as diabetic neuropathy, diabetic nephropathy, diabetic retinopathy, myocardial infarction, cataracts and diabetic cardiomyopathy.

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